(1.0 fl oz/29.6 ml)
Specially Formulated for Stubborn Or
Janson Beckettís AlphaDerma CE remains
unsurpassed at treating fine lines and
wrinkles on the face, neck, and body.
But while AlphaDerma CEís integrated approach
to fighting wrinkles and rejuvenating skin
reigns supreme, they have found a way to
enhance itís benefits by incorporating a
stronger spot wrinkle treatment into our skin
Introducing DermaExcel 7...the solution to
stubborn or hard-to-remove wrinkles. As
the understanding of the wrinkle formation
process continues to advance so does the
ability to impede this process. Wrinkles
and their formation due to facial expressions,
repetitive motions, environmental damage, and
natural aging are no longer considered
uncorrectable. Wrinkles have been proven
to be preventable and reversible.
Expression and repetitive motion wrinkles form
because of lingering skin tension produced
when excessive chemical signals stimulate
facial muscles. These types of wrinkles
can form each time you smile, frown, laugh or
cry. Repetitive movements can even occur
while you are asleep. Over time this
results in: brow lines (11s), forehead
creases, crowís feet, laugh lines, lip lines
around the mouth, and overall aging in the
appearance of the skin.
The cause of skin tension and muscle
contractions that form wrinkles relies on a
delicate neurotransmitter process called the
SNARE complex. The SNARE complex
involves three proteins (Snap 25, Vamp, and
Syntaxin) that combine to allow neurons to
complete exocytosis. Exocytosis is the
release of chemicals across the neuronís
synapse that triggers the contraction of a
muscle. Preventing or interrupting this
exocytosis is the key to stopping or
attenuating muscle contractions and hence
relaxing existing wrinkles and preventing new
ones from forming. Botulinum Toxin (BOTOXģ)
targets and stops this same process.
DermaExcel 7 is the first anti-wrinkle product
to combine the three latest most cutting-edge
peptides in a single spot wrinkle treatment.
DermaExcel 7 contains 5% PentaPeptide (Leuphasyl),
10% Acetyl HexaPeptide (Argireline), and 10%
HeptaPeptide (Snap-7), a Janson Beckett first.
Each peptide interrupts the wrinkle producing
SNARE complex differently but produces similar
and collaborative results...Reduced depth of
wrinkles and younger looking skin.
The PentaPeptide Leuphasyl works outside the
pre-synaptic neuron and prior to Argireline or
Snap-7. The body carries a slight
electrical charge. When the repetitive
movements occur, the electrical charge in that
part of the body rises. Leuphasyl helps
moderate the release of acetylcholine during
the SNARE complex by lowering the skinís
electrical charge in the applied area, making
it more difficult for neurons to fire.
Since neurons move the muscles by delivering
acetylcholine into the muscle cells,
Leuphasylís ability to moderate the electrical
charge being sent to the applied area is
crucial in lessening and relaxing muscle
contraction. Impairing muscle
contraction is what makes the skin look
younger and mitigates wrinkles and their
Acteyl HexaPeptide (Argireline) is a popular
ingredient in wrinkle cosmetics and was the
first peptide to offer effects similar to
BOTOX. Argireline works by mimicking a
component of the SNARE complex to block the
nerve signals and by inhibiting the
overproduction of catecholamines. By
blocking these neurotransmitters, Argireline
reduces the contraction of muscles and reduces
wrinkles and prevents wrinkle formation.
HeptaPeptide (Snap-7) is a natural amino acid
that contains seven amino peptides.
Snap-7ís advanced peptide structure is more
efficient at stopping vesicle formation and
neurotransmitter release than any other amino
peptide. Snap-7 is essentially the next
level of amino peptide that works faster and
reduces deeper wrinkles that the others could
not. Snap-7 accomplishes this by binding
to existing Snap-25 receptors to block the
release of acetylcholine. This prevents
neurons from effectively transmitting signals
that instruct muscles to contract. When
repetitive movements are impaired, the
formation of fine lines and wrinkles is
reduced or prevented.
The complementary system of Leuphasyl,
Argireline and Snap-7 makes DermaExcel 7ís
formula even more effective. Because
Leuphasyl lowers local synaptic voltage,
neuron responsiveness and efficiency is
lowered. Argireline and Snap-7 then work
in concert to intercept any neurotransmitters
actually released. This combined method
of treatment prevents and lessens muscle
contractions, subsequently reducing repetitive
or expressive wrinkle formation.
DermaExcel 7 combats your deep wrinkles and
augments the effects of AlphaDerma CE.
DermaExcel 7ís formula is an evolutionary step
in spot wrinkle prevention and repair targeted
at eliminating the final deep wrinkles that
resist AlphaDerma CE. By combining three
cutting-edge peptides, along with Alpha Lipoic
Acid, a powerful antioxidant, DMAE, a skin
firmer, and Shea Butter, a superior skin
moisturizer, Janson Beckett continues a
multi-faceted approach to anti-wrinkle and
anti-aging skin care.
Similar to its sibling AlphaDerma CE,
DermaExcel 7 can produce results immediately.
Test subjects reported seeing quick
improvements and commented they felt their
skin tighten and pleasantly tingle for up to
30 minutes after application. AlphaDerma
CE revolutionized wrinkle creams, and now
DermaExcel 7 is ready to safely but
aggressively eradicate your last stubborn or
hard-to-remove wrinkles. Although
DermaExcel 7 is a great stand-alone product
for wrinkles, the AlphaDerma CE sets the
skinís proper balance to further increase the
absorption and benefits of the DermaExcel 7.
Directions for stand-alone or with
AlphaDerma CE use:
1. Cleanse application area with warm water
and cleanser (we suggest using Janson
Beckettís Organic Cleansing Milk)
2. Apply DermaExcel 7 to hard to remove
wrinkle areas. For best results, use in
combination with and after applying AlphaDerma
When adding DermaExcel 7 to Janson
Beckettís anti-aging skin care regimen:
1. Cleanse application area with warm water
using Organic Cleansing Milk.
2. Apply Skin Toner sparingly to hands and pat
into face and throat. Let dry.
3. Apply AH3 HexaPeptide Facial Skin Prep and
4. Place a few drops of Vitamin C&C Facial
Serum on finger tips and pat gently around
eyes, forehead, cheeks, or wherever necessary.
5. Gently massage AlphaDerma CE into desired
area. Allow to absorb.
6. Apply DermaExcel 7 to hard to remove
wrinkle areas. Allow to absorb.
7. Optionally, apply a couple drops of OkuSil
to finger tips and pat lightly from the bridge
of nose outward under the eye area and above
the eye under the brow.
INGREDIENTS: Demineralized spring water, olive
oil, argireline (AH3 acetyl hexapeptide), snap
7 heptapeptide, glycerine, pentapeptides - 3,
cetearyl alcohol, ceteareth 20, shea butter,
soybean oil, alpha lipoic acid, milk thistle
extract, DMAE bitartrate, allantoin,
hydrolyzed soy protein, citric acid, carbomer
940, simethicone, caprylyl glycol,
phenoxyethanol, methylparaben, propylparaben,
ethylparaben, butylparaben, isobutylparaben,
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